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Nearly half of Tasmanians are unaware or deny that alcohol increases cancer risk, according to new research commissioned by the Alcohol and Other Drugs Council Tasmania (ATDC). While most recognise alcohol’s links to mental health, pregnancy and injury risks, 45% remain uninformed about its role in cancer, prompting calls for stronger public education campaigns.

“Our model serves as an important platform for understanding how chronic inflammation related to alcohol consumption accelerates the development of pancreatic cancer,” said Siddharth Mehra, Ph.D. Chronic alcohol use damages pancreatic acinar cells, increasing inflammation and leading to precancerous lesions. Knocking out CREB halted this progression, suggesting CREB inhibitors may offer therapeutic potential.