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New research from Columbia University Mailman School of Public Health and partners finds that alcohol consumption is associated with increased health risks even at levels often considered moderate, with no overall protective effect observed at low levels of drinking.

Heavy lifetime alcohol use significantly increases the risk of colorectal cancer, especially rectal cancer, according to a major U.S. screening trial. Consistent heavy drinking across adulthood was linked to a 91% higher risk, while former drinkers showed no elevated risk—suggesting that quitting alcohol may help reduce long-term cancer risk.